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Guys need zinc

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Erectile dysfunction ED is one of the most common sexual problems that men deal with. There are a host of different causes of ED that range from nutrient deficiencies to clinical depression. That said, erectile dysfunction has been found in recent years to be a symptom of zinc deficiency. Low levels of zinc can be the cause for a variety of health-related problems.

SEE VIDEO BY TOPIC: ZINC: Should VEGANS be worried? Or omnivores? (Why you may want to supplement)


Can zinc help treat erectile dysfunction?

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Our investigation showed that Zn contained many unique properties in human, especially males. The antioxidant quality is one of them. Also, the increased reactive oxygen species levels in the seminal plasma of men who are both infertile and smokers influence the Zn content of seminal plasma in a way that physiology of spermatozoa can be affected as well.

Moreover, Zn acts as a toxic repercussionagainst heavy metals and cigarette inflammatory agents. It plays a role in epithelial integrity, showing that Zn is essential for maintaining the lining of the reproductive organs and may have a regulative role in the progress of capacitation and acrosome reaction. In contrast, Zn deficiency impedes spermatogenesis and is a reason for sperm abnormalities and has a negative effect on serum testosterone concentration. Based on these findings, Zn microelement is very essential for male fertility.

It could be considered as a nutrient marker with many potentials in prevention, diagnosis, and treatment of male infertility. Sexual accessory glands secrete in the seminal plasma containing some elements that protect spermatozoa at the time of ejaculation 1. Zn is a plentiful microelement in the body and it is found in nuts, legumes 3 , seafood e.

Oysters , fortified cereals, cremini mushrooms, low-fat yogurt 4 and animal proteins, such as meat, fish and milk. Some reports showed that consumption of these natural foods can enhance germinal cell proliferation 5 , and poor Zn nutrition may be an important risk factor for the low quality of sperm and idiopathic male infertility 6.

Dietary Zn deficiency less than 5 ppm impairs reproduction in males and females. Zn has many important functions in the spermatozoa physiology, including effects on lipid flexibility and sperm membrane stabilization It also has a regulated role in capacitation and the acrosome reaction of sperm and is essential for conception and embryonic implantation Proteins containing Zn and selenium in mammalian spermatozoa are involved in modulating the amount of reactive oxygen species ROS ; therefore, it is interesting to investigate whether balanced amounts of Zn and other oligoelements that are added to the semen diluent would moderate the deleterious effects of ROS on chromatin structure Contreras et al.

In our previous study, it was demonstrated that an important risk factor for low quality of sperm and idiopathic male infertility is poor Zn nutrition 6. But in this review, the focus was on the various roles of Zn in male health, reproductive system, quality and function of sperm, as well as the effects of epigenetic factors on Zn and finally the molecular and cellular mechanisms of Zn.

The nearby organs include prostate, liver, the gastrointestinal tract; kidney, skin, lung, adrenals, brain, heart, eyes and pancreas contain estimable concentrations of Zn. Blood tests for Zn deficiency are inaccurate because majority of Zn is cumulative inside cells and is not free in the blood. Assisting immune function, patronage of healthy cell growth, having a role in preserving prostate health, sexual health and testosterone hormone levels are typical examples.

It has been demonstrated that Zn plays a significant role in reproductive functions 14 , Hosseinzadeh Colager et al. The level of Zn in fertile men was There are many reports that showed reduction or increase in consumption of Zn which let to overindulge vis-a-vis deficiency damages in many of the human organs Table 1. For example, Zn deficiency is correlated with reduction in testis volume, a decrease in testicular weight, hypogonadism, gonadal dysfunction, inadequate development of secondary sex specifications in human, shrinkage of seminiferous tubules, the failure of spermatogenesis, male gonad growth and hypogonadism 8.

And so, there are many reports for Zn-physiological roles in human Table 2 , including its role in gonads- and some enzyme-functions, treatments of some diseases, and better function of apoptosis and immune systems. Some of these Zn-physiological roles are indicated below. Zn contains many roles in the immune systems Table 3. Zn has a role in almost all aspects of inherent immunity and compatibility, so Zn deficiency may influence weakening of immune system and reproductive system.

Zn is effective in various mechanisms, including DNA replication, RNA transcription, proliferation, and differentiation and activation of immune cells in many organs of the body 9 , 10 , The innate as well as the specific parts of the immune system are influenced by Zn.

The effects of Zn are multifaceted. Zn can induce adhesion of myelomonocytic cells to the endothelium, while Zn chelation diminishes cell recruitment. Thus, Zn is essential, even in the earliest stages of an immune response. At the molecular level, Zn is required for the interaction between the p58 killer cell inhibitory receptor on NK cells and major histocompatibility complex MHC class I molecules, mainly human leukocyte antigen C, on target cells, resulting in the inhibition of the killing activity 8.

Interestingly, Zn is needed to maintain the normal function of natural killer cells, and Zn deficiency may result in non-specific killing activity and functional loss. In addition to effects of upstream signaling molecules, Zn influences gene expression by structural stabilization and functional regulation of various immunological-relevant transcription factors as summarized earlier Zn corrects these adverse effects of cadmium on the immune system and biochemical processes as a component of the antioxidant superoxide dismutase and protects the testicular endothelium and sperm cell membranes Zn exists at high levels in the testis of vertebrates which are comparable to liver and kidney.

Moreover, there are certain reports that manifest Zn can reduce testis injury by stresses such as heavy metals, fluoride, and heat Zn is assembled in the testis during early spermatogenesis and may play a main role in the adjustment of the spermatogonial reproduction and in the meiosis of germ cells Mostly, Zn assembles in germ cells and its concentration in testis increments during spermatogenesis.

Some researchers have witnessed that Zn is needed for the normal functioning of the hypothalamus-pituitary-gonadal axis. Because of the important role of Zn in male reproductive potential, it is paramount to recognize that andrological variations which are most sensitive to Zn depletion.

An evaluation of those variables in clinical cases of possible Zn deficiency would accelerate treatment. Zn influences male fertility in several different ways. Low Zn levels have a negative effect on serum testosterone concentration Thyroid hormones have several important roles in the body including metabolism, development and even body temperature.

Zn helps the body maintain proper thyroid function by producing hormones in the brain called thyroid-releasing hormones. Whenever men are low in Zn, they may fail to produce enough of these hormones. That can also affect testosterone levels 4. Seminal Zn is considered as an indicator of prostatic function; however, the function of Zn in seminal plasma and semen is unknown. Most Zn secreted from the prostate in humans seems to target the proteins secreted from seminal vesicle. Other research shows that the Zn and albumin secreted from the prostate constitute a complex that covers the sperm and thereby protects the cells Zn is situated primarily in the Leydig cells, the late type B spermatogonia, and the spermatids.

And also is vital for the production and secretion of testosterone from the Leydig cells. Zn in human semen seems to play an important role in the physiology of spermatozoa. On the other hand, there is remarkable evidence that Zn deficiency causes primary testicular failure, lessens function of the luteinizing hormone receptor, lessens steroid synthesis and Leydig cell damage due to oxidative stress The prostate compared to other tissues and body fluids has high concentration of Zn.

Actually, Zn is a marker of prostatic function. Its other roles are regulation of the functions of spermatozoa, acting as a co-factor for most enzymatic reactions, and helping in preservation of sperm motility Zn as a downward molecular weight complex with citrate or bound to glycoproteins of the sperm vesicles is discharged from the prostate demonstrating that biologic Zn therapy has a positive effect on sperm motility and the use of biologic Zn supplementation was an efficient method for the treatment of infertile males with chronic prostatitis Zn oxide nanoparticles have bactericidal effects on both gram-positive and gram-negative bacteria and are also effective against spores which are resistant to high temperature and high pressure 28 , Prostatic Zn may have antibacterial activity because trichomonas vaginalis is easily killed at concentrations of Zn that occur in the prostatic fluid of healthy men Furthermore, Zn has antibacterial activity and antilipid peroxidation properties that maintain sperm membrane stability and protect the testis against the degenerative changes Evidence suggests that seminal Zn has an important role in the physiologic functions of the sperm and that its reduced levels result in low seminal quality and subsequent chances of fertilization 6.

Zn is known to be essential for sexual maturity and onset of estrus. Zn plays a role in epithelial integrity, showing that Zn is essential for maintaining the lining of the reproductive organs 6.

Furthermore, it has an important role in stabilizing the cell membrane and nuclear chromatin of spermatozoa in seminal plasma. It may have a regulative role in the progress of capacitation and acrosome reaction. The Zn concentration in human seminal plasma is higher than in other tissues Zn has been shown to be vital for spermatogenesis.

It plays a significant role in testis development and sperm physiologic functions 6. Zn contains a variety of roles in the spermatogenesis phases Table 4. For example, in the initiation of spermatogenesis, Zn is important in participation of ribonuclease activities that is highly active during mitosis of spermatogonia and meiosis of spermatocytes. During spermatogenesis, spermatids obtain tail and motility with a developed mid-piece which connects the head compartment with the tail. This physical maturation process occurs in seminiferous tubule.

Sperm maturation and storage happens in the epididymis. At the end of spermatogenesis, Zn is highly concentrated in the tail of mature spermatozoa and involved in sperm motility Though the dynamics of Zn during sperm expansion is far to be ambiguous but, the significant role of Zn in normal spermatogenesis and sperm suitability is known.

Foresta et al. Optimal concentrations of Zn in the seminal plasma have also been related to an increase in sperm concentration of the ejaculate 11 , high motility, viability 32 and enhancing antioxidant activity A low concentration of Zn has been indicated to disturb the fatty acid composition of the testis and interfere with normal endocrine regulation of the testis Zn is associated with catabolism of lipid that is done in sperm middle piece and provides energy for motion of spermatozoa.

Testicular Zn is crucial for normal spermatogenesis and for sperm physiology; it maintains genomic integrity in the sperm and fixes attachment of sperm head to tail Zn ions can increase male fertility by regulation of the expression of testis GC-specific genes during the differentiation process and spermatogenesis 35 , Also Zn therapy reduced asthenozoospermia Supra-nutritional doses of Zn, Co, and Se were used to enhance the production of motile sperm with intact membranes The negative correlation between seminal plasma Zn and sperm viability is a good sign of the importance of Zn in spermatogenesis This may be clarified by the necessary role of Zn in protein metabolism and nucleic acid synthesis.

Alteration of seminal plasma Zn changes count, motility, viability, pH and viscosity. Seminal plasma Zn-T Zn per ejaculate is the better marker for assessing the relationship between Zn and semen quality Low seminal Zn levels have been related with decreased fertility potential. However, other authors reported that normozoospermic and oligoasthenozoospermic patients had similar seminal plasma Zn concentrations Akinloye et al. There is extensive evidence that human seminal Zn has an important role in the physiologic sperm functions and Zn reduced levels led to low quality of sperm and reduced fertilization chances.

Some authors have reported that high Zn concentration are correlated with enhanced sperm parameters, including sperm count, motility, and normal morphology 11 , 12 , 42 , whereas in Danscher et al.

Connecting Testosterone and Zinc

Testosterone levels peak during early adulthood, and then begin to drop as a part of the natural aging process. If your testosterone levels fall below the normal range, you may have a condition called hypogonadism. Hypogonadism can result from several treatable medical conditions.

The dietary supplement business is a multibillion-dollar industry. You can buy supplements in virtually every supermarket and drugstore in America, to say nothing of the growing number of health food stores and "body shops" that specialize in them.

Zinc is a trace mineral that plays a vital role in many aspects of human health. These processes include growth, immunity, and reproduction. It helps the body produce and regulate many hormones including testosterone. Some studies have shown a link between not having enough zinc and erectile dysfunction ED.

The Link Between Zinc and Erectile Dysfunction

Zinc is a fantastic supplement for everyone, but a few of its functions may be of particular interest to men! Did you know it can help to balance testosterone levels and support a healthy prostate? Jen Tan. Zinc has a number of vital functions, from supporting the immune system and promoting wound healing, to supporting healthy bones, skin and vision. It even acts as an antioxidant to protect cells from oxidative stress! However, there are a few functions of zinc that may be of particular interest to men. Low testosterone can cause all kind of unpleasant effects such as low libido, fatigue, loss of muscle mass, or even erectile dysfunction. There are a number of reasons why your testosterone levels might drop, from certain medications to genes and age.

4 reasons why men need more zinc in their diets

Our investigation showed that Zn contained many unique properties in human, especially males. The antioxidant quality is one of them. Also, the increased reactive oxygen species levels in the seminal plasma of men who are both infertile and smokers influence the Zn content of seminal plasma in a way that physiology of spermatozoa can be affected as well. Moreover, Zn acts as a toxic repercussionagainst heavy metals and cigarette inflammatory agents.

Guys, are you up to speed when it comes to vitamins and minerals from A to Z? If so, then it shouldn't come as a surprise that zinc plays an essential role in our bodies.

Clue number two: zinc has an impact on testosterone levels, and we all know how important that is! Zinc is an essential trace mineral that is necessary for all cells. Prostate cells, however, accumulate more zinc than cells anywhere else in the body. In addition to the prostate, zinc is found in high concentrations in bone, eyes, kidney, liver, muscles, and pancreas.


This means that your body must require it and cannot produce it… you have to get zinc from foods or supplements. Zinc plays a number of roles in our body, including promoting immune defence and healing wounds. Prostate health is an uncomfortable topic for most men, and if you have a prostate problem, things get even more uncomfortable when you have to go and see your doctor. However, given that prostate cancer is the sixth highest killer of men in Australia figures , taking prostate health seriously is important.

When it comes to minerals and nutrients we tend to look at them from A-Z. Some of you may have heard about the eyesight benefits of getting enough Vitamin A, the energy benefits of supporting Vitamin B12, and the immune boosting benefits of supplementing with Vitamin C. However, we cannot forget to look at one of the last minerals of our A-Z list, Zinc. Zinc, although alphabetically low on the list, is one of the most common minerals and it is found in soil, air, water and is present in all of our foods. Zinc became well known after zinc lozenges became popular to help boost your immune system during an illness.

Zinc and prostate cancer


Mar 9, - Zinc also enables the male body to produce testosterone. Certain vegetables, meats, and seafood have more zinc content than others.‎Zinc Deficiency · ‎Risk Factors · ‎Zinc Deficiency and Erectile · ‎ED Treatment.


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Comments: 2
  1. Shaktinos

    Bravo, you were visited with a remarkable idea

  2. Kazragal

    You are mistaken. Let's discuss.

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